It's only happened once. And the latest online odds think that 1 will remain the loneliest number. Online odds do not believe Louisville QB Lamar Jackson will not repeat as Heisman Trophy Champion. Last season he torched opponents en route to the 2016 Heisman Trophy. He currently sit at No. 3 in Bovada’s odds to win this year’s award. Right now Florida St. signal caller Deonadre Francois is stands at 12-1.